{"id":2258,"date":"2026-03-12T07:14:38","date_gmt":"2026-03-12T07:14:38","guid":{"rendered":"https:\/\/staging.ccomdigital.in\/client\/mitoswab\/website\/?page_id=2258"},"modified":"2026-05-14T12:03:21","modified_gmt":"2026-05-14T12:03:21","slug":"faqs","status":"publish","type":"page","link":"https:\/\/www.mitoswab.com\/staging\/faqs\/","title":{"rendered":"FAQs"},"content":{"rendered":"\t\t
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FAQs<\/h1>

For your convenience, we have compiled a list of Frequently Asked Questions.\nPlease see below.<\/p>\t\t<\/div>\n\t\t\t\t\t

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\"AboutAbout the Test<\/h2>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t
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What is MitoSwab\u2122<\/sup><\/b>? <\/div><\/span>\n\t\t\t\t\t\t\t\n\t\t\t<\/path><\/svg><\/span>\n\t\t\t<\/path><\/svg><\/span>\n\t\t<\/span>\n\n\t\t\t\t\t\t<\/summary>\n\t\t\t\t
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MitoSwab\u2122<\/sup><\/strong> is a non-invasive test that analyzes the power of the mitochondria. With a simple buccal mucosal swab, MitoSwab\u2122<\/sup> will analyze the components of the Electron Transport Chain. Additionally, it measures Citrate Synthase activity, which provides an indicator of the overall mitochondrial content within the cells.<\/p>\nMitoSwab\u2122<\/sup><\/strong> has an 84% correlation with the muscle biopsy, which is the current gold standard for the evaluation of mitochondrial dysfunction. The ease of using a buccal swab makes MitoSwab\u2122<\/sup><\/strong> the first choice for the exploratory investigation of mitochondrial dysfunction.\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/details>\n\t\t\t\t\t\t

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Do I need to stop my supplements before testing? <\/div><\/span>\n\t\t\t\t\t\t\t\n\t\t\t<\/path><\/svg><\/span>\n\t\t\t<\/path><\/svg><\/span>\n\t\t<\/span>\n\n\t\t\t\t\t\t<\/summary>\n\t\t\t\t
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Yes. Please stop all supplements at least 7 days before<\/strong> your test \u2014 this is called a wash-out period. The supplements which affect mitochondria are both water soluble and lipid soluble with different bioavailability half-lives. If a patient can’t have a wash out period, then the existing treatment may be considered baseline.<\/p>\n

Supplements known to affect mitochondrial function include: \n<\/p>\n

CoQ10,<\/strong><\/p>\n

L-Carnitine,<\/strong><\/p>\n

Alpha Lipoic Acid,<\/strong><\/p>\n

PQQ,<\/strong><\/p>\n

NADH.<\/strong><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/details>\n\t\t\t\t\t\t

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What does the sample actually test \u2014 DNA, RNA, or something else? <\/div><\/span>\n\t\t\t\t\t\t\t\n\t\t\t<\/path><\/svg><\/span>\n\t\t\t<\/path><\/svg><\/span>\n\t\t<\/span>\n\n\t\t\t\t\t\t<\/summary>\n\t\t\t\t
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\n\t\t\t\t\t\t\t\t\tThe MitoSwab\u2122<\/sup> is a buccal (cheek) swab, not a saliva sample. It is a functional test that analyzes how well your mitochondria are working \u2014 it does not test your DNA or genetics.\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/details>\n\t\t\t\t\t\t
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What are mitochondria? <\/div><\/span>\n\t\t\t\t\t\t\t\n\t\t\t<\/path><\/svg><\/span>\n\t\t\t<\/path><\/svg><\/span>\n\t\t<\/span>\n\n\t\t\t\t\t\t<\/summary>\n\t\t\t\t
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\n\t\t\t\t\t\t\t\t\tMitochondria are organelles in the cells that produce energy to power the cell. In\nother words, they produce energy (ATP) which is the energy currency of the cell\nneeded for all bodily functions. They also have their own DNA, which makes\nthem highly dynamic. Otherwise known as the \u201cpower plants\u201d of the body, their\nproper function is critical for overall health and longevity.\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/details>\n\t\t\t\t\t\t
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How would MitoSwab\u2122<\/sup><\/b> help the patient? <\/div><\/span>\n\t\t\t\t\t\t\t\n\t\t\t<\/path><\/svg><\/span>\n\t\t\t<\/path><\/svg><\/span>\n\t\t<\/span>\n\n\t\t\t\t\t\t<\/summary>\n\t\t\t\t
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\n\t\t\t\t\t\t\t\t\tMitoSwab\u2122<\/sup><\/strong> is a helpful tool used in the diagnosis of mitochondrial dysfunction. It\nis also a valuable tool that can be used to monitor therapy. MitoSwab\u2122<\/sup><\/strong> has a\ncorrelation of 84% to the muscle biopsy, considered the gold standard for the\ndiagnosis of mitochondrial dysfunction. The muscle biopsy, however, is\ninvasive. MitoSwab\u2122<\/sup><\/strong> provides an excellent alternative as a potential first line test\nfor mitochondrial dysfunction.\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/details>\n\t\t\t\t\t\t
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What is a buccal swab? <\/div><\/span>\n\t\t\t\t\t\t\t\n\t\t\t<\/path><\/svg><\/span>\n\t\t\t<\/path><\/svg><\/span>\n\t\t<\/span>\n\n\t\t\t\t\t\t<\/summary>\n\t\t\t\t
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\n\t\t\t\t\t\t\t\t\tA buccal swab is a simple swab of the inside of the cheek. MitoSwab\u2122<\/sup><\/strong> requires 2\nswabs of both the right and left check. It is a simple procedure that is quick and\neasy to perform. It can be done at home and at your convenience.\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/details>\n\t\t\t\t\t\t
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How do I collect the sample? <\/div><\/span>\n\t\t\t\t\t\t\t\n\t\t\t<\/path><\/svg><\/span>\n\t\t\t<\/path><\/svg><\/span>\n\t\t<\/span>\n\n\t\t\t\t\t\t<\/summary>\n\t\t\t\t
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\n\t\t\t\t\t\t\t\t\tPlease see the instructions included in the MitoSwab\u2122 kit. Also, you may find the\nsample collection information on our website at: Sample Collection Form<\/a>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/details>\n\t\t\t\t\t\t
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Do I have to fast before collecting a sample? <\/div><\/span>\n\t\t\t\t\t\t\t\n\t\t\t<\/path><\/svg><\/span>\n\t\t\t<\/path><\/svg><\/span>\n\t\t<\/span>\n\n\t\t\t\t\t\t<\/summary>\n\t\t\t\t
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\n\t\t\t\t\t\t\t\t\tNo, you do not need to fast prior to collecting a sample.\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/details>\n\t\t\t\t\t\t
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Do I have to wash my mouth before collecting the sample? <\/div><\/span>\n\t\t\t\t\t\t\t\n\t\t\t<\/path><\/svg><\/span>\n\t\t\t<\/path><\/svg><\/span>\n\t\t<\/span>\n\n\t\t\t\t\t\t<\/summary>\n\t\t\t\t
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\n\t\t\t\t\t\t\t\t\tYes, it is preferred to rinse your mouth with water prior to a sample collection.\nPlease don\u2019t use mouthwash or any type of alcohol to rinse.\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/details>\n\t\t\t\t\t\t
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Do I have to be off any medications\/supplements before collecting a sample? <\/div><\/span>\n\t\t\t\t\t\t\t\n\t\t\t<\/path><\/svg><\/span>\n\t\t\t<\/path><\/svg><\/span>\n\t\t<\/span>\n\n\t\t\t\t\t\t<\/summary>\n\t\t\t\t
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\n\t\t\t\t\t\t\t\t\tSome medications\/supplements may affect the mitochondrial function. Please\nconsult your health care practitioner for guidance.<\/strong> It is advised to document\nthe list of the medications before collecting the sample.\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/details>\n\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t
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\"Logistics\"Logistics<\/h2>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t
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Is a return shipping label included with my kit? <\/div><\/span>\n\t\t\t\t\t\t\t\n\t\t\t<\/path><\/svg><\/span>\n\t\t\t<\/path><\/svg><\/span>\n\t\t<\/span>\n\n\t\t\t\t\t\t<\/summary>\n\t\t\t\t
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Yes. The Mitoswab\u2122<\/sup> kit includes an overnight return label and is included in the pricing for domestic and Canada patients. Detailed shipping and sample storage instructions are included with the kit and provided at the time of ordering<\/p>\n

Please note that NOT following the shipping and sample storage instructions accurately can seriously affect the quality of the sample and the accuracy of the test results.<\/strong><\/p>\n

DO NOT SHIP on a Friday<\/strong> or prior to a holiday.Holiday schedule inquiries can be emailed to support@mitoswab.com.<\/a><\/p>\nDO NOT USE YOUR OWN SHIPPING LABEL<\/strong>-Mitochondrial samples are temperature sensitive and require overnight shipping.\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/details>\n\t\t\t\t\t\t

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Do you ship internationally? <\/div><\/span>\n\t\t\t\t\t\t\t\n\t\t\t<\/path><\/svg><\/span>\n\t\t\t<\/path><\/svg><\/span>\n\t\t<\/span>\n\n\t\t\t\t\t\t<\/summary>\n\t\t\t\t
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Yes, we work with international clients depending on location. Dry ice requirements apply for international shipments.<\/p>\nPlease contact our customer support team at support@mitoswab.com<\/a> for international shipping instructions and kit delivery options before ordering.\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/details>\n\t\t\t\t\t\t

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Where do I send the sample? <\/div><\/span>\n\t\t\t\t\t\t\t\n\t\t\t<\/path><\/svg><\/span>\n\t\t\t<\/path><\/svg><\/span>\n\t\t<\/span>\n\n\t\t\t\t\t\t<\/summary>\n\t\t\t\t
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The MitoSwab\u2122<\/sup><\/strong> kit contains a return envelope to send in your sample. The
address for MitoSwab\u2122<\/sup><\/strong> is:<\/p>\n

ReligenDx
5110 Campus Drive, Suite #120
Plymouth Meeting, PA 19462  <\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/details>\n\t\t\t\t\t\t

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Do you accept samples from international patients? <\/div><\/span>\n\t\t\t\t\t\t\t\n\t\t\t<\/path><\/svg><\/span>\n\t\t\t<\/path><\/svg><\/span>\n\t\t<\/span>\n\n\t\t\t\t\t\t<\/summary>\n\t\t\t\t
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Please send us a note at support@mitoswab.com<\/a> and we will be in touch with you as soon as possible to address logistics.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/details>\n\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t

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\"BillingBilling and Insurance<\/h2>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t
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What are the CPT codes so I can check my insurance coverage? <\/div><\/span>\n\t\t\t\t\t\t\t\n\t\t\t<\/path><\/svg><\/span>\n\t\t\t<\/path><\/svg><\/span>\n\t\t<\/span>\n\n\t\t\t\t\t\t<\/summary>\n\t\t\t\t
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\n\t\t\t\t\t\t\t\t\tThe CPT codes for MitoSwab\u2122<\/sup> testing are 82657 and 84311. Diagnosis (dx) codes are provided by your ordering physician based on your clinical picture.\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/details>\n\t\t\t\t\t\t
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Do you accept insurance? How does payment work? <\/div><\/span>\n\t\t\t\t\t\t\t\n\t\t\t<\/path><\/svg><\/span>\n\t\t\t<\/path><\/svg><\/span>\n\t\t<\/span>\n\n\t\t\t\t\t\t<\/summary>\n\t\t\t\t
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We currently do not accept insurance for Mitoswab\u2122<\/sup> testing.<\/strong> Payment is due at the time of ordering.<\/p>

Patients have three options on your requisition form:<\/p>